Browsing: glioblastoma

All research was conducted in accordance with all relevant ethical regulations. GSC (-) and GSC (+) were established from a…

Glioblastoma (GBM) is a highly aggressive type of brain tumor characterized by diffuse infiltration and a profoundly immunosuppressive microenvironment in…

Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by a poor prognosis and limited therapeutic options. In this…

PatientsThe study was approved by the Institutional Ethics Committee (study approval numbers 108-39/4-2014-UVN and 7/8/2014-25) and conducted in accordance with…

ATRA suppresses terminal exhaustion and preserves effector function in CD8⁺ T cellsTo explore the factors that promote CD8+ T-cell exhaustion,…

Ethical statementWe confirm that the research performed in the present study complies with all ethical regulations. All animal experiments were…

Glioblastoma (GBM) remains one of the most aggressive human cancers, driven by cellular plasticity and dynamic interactions with the neurovascular…

Glioblastoma (GBM) remains the most aggressive primary adult brain cancer with limited therapeutic options. Our prior research demonstrated that androgen…

Cell cultureA172, LN229, U251, U87, HT1080, and 293T cells were cultured in DMEM (GIBCO, C11995500BT) supplemented with 10% Fetal Bovine…

Ethics statementsThe studies were performed in compliance with the guidelines approved by the Institutional Animal Care and Use Committee (IACUC)…