Author: NewsCancer

The 15-year-old is planning his father’s funeral while he is alive so he can fulfil his wishes.

Weekly episodes aim to share other people’s experiences to help people with cancer feel less alone.

Zou, A. E., Kongthong, S., Mueller, A. A. & Brenner, M. B. Fibroblasts in immune responses, inflammatory diseases and therapeutic implications. Nat. Rev. Rheumatol. 21, 336–354 (2025).Article  CAS  PubMed  Google Scholar  Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C. & Brown, R. A. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat. Rev. Mol. Cell Biol. 3, 349–363 (2002).Article  CAS  PubMed  Google Scholar  Buechler, M. B. & Turley, S. J. A short field guide to fibroblast function in immunity. Semin. Immunol. 35, 48–58 (2018).Article  CAS  PubMed  Google Scholar  Smillie, C. S. et al. Intra- and inter-cellular rewiring of the human…

A Chelsea Flower Show garden has been inspired by a Jersey woman who died from ovarian cancer

Libby Woolaston says her headaches were blamed on stress and children before brain cancer diagnosis.

Researchers at the University of Lausanne (Unil) have uncovered a new biological mechanism that exposes a critical vulnerability in tumor cells when they are deprived of vitamin B7. All cells must adjust to changes in nutrient supply to survive. However, some cells become especially reliant on glutamine, an amino acid that plays a major role in metabolism. Glutamine provides essential components needed to build proteins and DNA, and without it, cells cannot continue to grow and divide. Cancer cells are a prime example. Many tumors exhibit what scientists call “glutamine addiction,” meaning they depend heavily on this nutrient. Although this…

Profiling the activity of clinical kinase inhibitors in wild-type kinasesWe screened 92 clinical kinase inhibitors (Supplementary Table 1 and Supplementary Fig. 1) across a panel of 758 kinases, including 409 wild-type kinases and 349 mutant kinases or kinase fusion products. Of the 92 inhibitors, 86 are FDA approved, one is approved by the National Medical Products Administration and five are in late-stage clinical trials. Of the approved drugs, two have since been discontinued and three have been withdrawn from the market. This screen used the HotSpot radiometric filter-binding kinase assay, a functional approach that directly quantifies the kinase-mediated transfer of…

Expression and clinical correlation analysis of MCT4 (SLC16A3) across cancersUALCAN (http://ualcan.path.uab.edu) is an open platform designed for user-friendly analysis of data from TCGA and CPTAC databases. We used UALCAN to conduct a pan-cancer analysis of SLC16A3 at both the transcriptional and protein levels, using TCGA and CPTAC data, respectively, with the gene specified as “SLC16A3” and the assay set to “Pan-Cancer Review.” To further investigate the expression of SLC16A3 in breast cancer, the cancer type was set to “breast cancer,” and the assay method to “expression assay.” Patients with breast carcinoma in TCGA and CPTAC were further stratified by stage…

Angus Chen covers all issues broadly related to cancer including drugs, policy, science, and equity. He joined STAT in 2021 after covering health and science at NPR and NPR affiliate stations. His work has been recognized by national Edward R. Murrow awards, the June L. Biedler prize for cancer journalism, and more. You can reach Angus on Signal at angus.08.Damian Garde is a reporter at large, live and feature journalism, covering the global drug industry and contributing to STAT’s industry-leading events.You’re reading the web version of STAT’s popup newsletter, AACR in 30 seconds, your guide to what’s happening at the…

Angus Chen covers all issues broadly related to cancer including drugs, policy, science, and equity. He joined STAT in 2021 after covering health and science at NPR and NPR affiliate stations. His work has been recognized by national Edward R. Murrow awards, the June L. Biedler prize for cancer journalism, and more. You can reach Angus on Signal at angus.08.SAN DIEGO — Alison Cameron spent close to a decade fighting to keep myeloma under control. She’d been diagnosed with smoldering multiple myeloma, a precursor to cancer, and spent years receiving infusions to keep it from progressing to active multiple myeloma.…