Villanueva A, Longo DL. Hepatocellular carcinoma. N Engl J Med. 2019;380:1450–62.
Google Scholar
Llovet JM, Pinyol R, Kelley RK, El-Khoueiry A, Reeves HL, Wang XW, et al. Molecular pathogenesis and systemic therapies for hepatocellular carcinoma. Nat Cancer. 2022;3:386–401.
Google Scholar
Liu C-X, Chen L-L. Circular RNAs: characterization, cellular roles, and applications. Cell. 2022;185:2016–34.
Google Scholar
Dong JN, Zeng ZE, Huang Y, Chen CP, Cheng ZE, Zhu QB. Challenges and opportunities for circRNA identification and delivery. Crit Rev Biochem Mol. 2023;58:19–35.
Google Scholar
Huang Y, Ji H, Dong J, Wang X, He Z, Cheng Z, et al. CPSF3 promotes Pre-mRNA splicing and prevents CircRNA cyclization in hepatocellular carcinoma. Cancers. 2023;15:4057.
Youness RA, Hassan HA, Abaza T, Hady AA, El Magdoub HM, Ali M, et al. A comprehensive insight and in silico analysis of CircRNAs in hepatocellular carcinoma: a step toward ncRNA-based precision medicine. Cells. 2024;13:1245.
Enuka Y, Lauriola M, Feldman ME, Sas-Chen A, Ulitsky I, Yarden Y. Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor. Nucleic Acids Res. 2016;44:1370–83.
Google Scholar
Dong J, Zeng Z, Sun R, Zhang X, Cheng Z, Chen C, et al. Specific and sensitive detection of CircRNA based on netlike hybridization chain reaction. Biosensors and Bioelectronics. 2021;192:113508.
He Z, Zhu Q. Circular RNAs: emerging roles and new insights in human cancers. Biomed Pharmacother. 2023;165:115217.
Conn VM, Chinnaiyan AM, Conn SJ. Circular RNA in cancer. Nat Rev Cancer. 2024;24:597–613.
Google Scholar
Wang X, Dong J, Li X, Cheng Z, Zhu Q. CPSF4 regulates circRNA formation and microRNA mediated gene silencing in hepatocellular carcinoma. Oncogene. 2021;40:4338–51.
Google Scholar
Li X, Ding J, Wang X, Cheng Z, Zhu Q. NUDT21 regulates circRNA cyclization and ceRNA crosstalk in hepatocellular carcinoma. Oncogene. 2019;39:891–904.
Google Scholar
Qu S, Yang X, Li X, Wang J, Gao Y, Shang R, et al. Circular RNA: a new star of noncoding RNAs. Cancer Lett. 2015;365:141–8.
Google Scholar
Huang Y, Zhu Q. Mechanisms regulating abnormal circular RNA biogenesis in cancer. Cancers. 2021;13:4185.
Zhang X-O, Wang H-B, Zhang Y, Lu X, Chen L-L, Yang L. Complementary sequence-mediated exon circularization. Cell. 2014;159:134–47.
Google Scholar
Liang D, Wilusz JE. Short intronic repeat sequences facilitate circular RNA production. Genes Dev. 2014;28:2233–47.
Google Scholar
Cao D. Reverse complementary matches simultaneously promote both back-splicing and exon-skipping. BMC Genomics. 2021;22:586.
He Z, Ji H, Xia B, Cao X, Huang Y, Zhu Q. Invention of circRNA promoting RNA to specifically promote circRNA production. Nucleic Acids Res. 2024;52:e83.
Google Scholar
Bourgeois CF, Mortreux F, Auboeuf D. The multiple functions of RNA helicases as drivers and regulators of gene expression. Nat Rev Mol Cell Biol. 2016;17:426–38.
Google Scholar
Pavan Umate NT, Renu T. Genome-wide comprehensive analysis of human helicases. Commun Integr Biol. 2011;4:118–37.
Liang Y, Wang H, Chen B, Mao Q, Xia W, Zhang T, et al. circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression. Mol Ther Nucleic Acids. 2021;23:355–68.
Google Scholar
Yu J, Xu Q-g, Wang Z-g, Yang Y, Zhang L, Ma J-z, et al. Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma. J Hepatol. 2018;68:1214–27.
Google Scholar
Yang D, Hu Z, Xu J, Tang Y, Wang Y, Cai Q, et al. MiR-760 enhances sensitivity of pancreatic cancer cells to gemcitabine through modulating Integrin β1. Biosci Rep. 2019;39:BSR20192358.
Yang L, Shen A, Wang R, Zheng Z. S100A16 stabilizes the ITGA3‑mediated ECM‑receptor interaction pathway to drive the malignant properties of lung adenocarcinoma cells via binding MOV10. Mol Med Rep. 2024;31:11.
Messaoudi-Aubert SE, Nicholls J, Maertens GN, Brookes S, Bernstein E, Peters G. Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor. Nat Struct Mol Biol. 2010;17:862–8.
Google Scholar
Mao CG, Jiang SS, Shen C, Long T, Jin H, Tan QY, et al. BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A. Thorac Cancer. 2020;11:3326–36.
Google Scholar
He Q, Zhao L, Liu X, Zheng J, Liu Y, Liu L, et al. MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change. J Exp Clin Cancer Res. 2019;38:9.
Huang H, Lu R, Peng S, Huang S, Mo Y, Li G. PIWIL genes in hepatocellular carcinoma: a multi-omics approach uncovering dysregulated expression and ceRNA networks in mice. BMC Genom Data. 2024;25:101.
Google Scholar
Yan J, Wu L-G, Zhang M, Fang T, Pan W, Zhao J-L, et al. miR‐328‐5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2. Oxid Med Cell Longev. 2022;2022:3511967.
Google Scholar
Liu J, Lichtenberg T, Hoadley KA, Poisson LM, Lazar AJ, Cherniack AD, et al. An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics. Cell. 2018;173:400–16.e11.
Google Scholar
Győrffy B. Integrated analysis of public datasets for the discovery and validation of survival-associated genes in solid tumors. Innovation. 2024;5:100625.
Glažar P, Papavasileiou P, Rajewsky N. circBase: a database for circular RNAs. Rna. 2014;20:1666–70.
Google Scholar
Sun L, Dong S, Ge Y, Fonseca JP, Robinson ZT, Mysore KS, et al. DiVenn: an interactive and integrated web-based visualization tool for comparing gene lists. Front Genet. 2019;10:421.
Yin T-F, Zhao D-Y, Zhou Y-C, Wang Q-Q, Yao S-K. Identification of the circRNA-miRNA-mRNA regulatory network and its prognostic effect in colorectal cancer. World J Clin Cases. 2021;9:4520–41.
Google Scholar
Wei B, Xiao S, Lou W. In silico whole-transcriptome analysis reveals a potential hsa_circ_0000375-miR-424-5p-TPM2/SRPX/SRGAP1 regulatory network related to liver metastasis of colorectal cancer. Heliyon. 2023;9:e21688.
Liang L, Gao M, Li W, Tang J, He Q, Zeng F, et al. CircGSK3β mediates PD-L1 transcription through miR-338-3p/PRMT5/H3K4me3 to promote breast cancer cell immune evasion and tumor progression. Cell Death Discovery. 2024;10:426.
Qian C-j, Zhou Y-x, Wu L-k, Wang Y-c, Teng X-s, Yao J. Circ_0000182 promotes cholesterol synthesis and proliferation of stomach adenocarcinoma cells by targeting miR-579-3p/SQLE axis. Discover Oncol. 2023;14:22.
Guo W, Zhang B, Mu K, Feng S-Q, Dong Z-Y, Ning G-Z, et al. Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk. Cell Death Disease. 2018;9:319.
Liu Z, Yu Y, Huang Z, Kong Y, Hu X, Xiao W, et al. CircRNA-5692 inhibits the progression of hepatocellular carcinoma by sponging miR-328-5p to enhance DAB2IP expression. Cell Death Disease. 2019;10:900.
Zhang L, Zhang Y, Zhu H, Sun X, Wang X, Wu P, et al. Overexpression of miR-301a-3p promotes colorectal cancer cell proliferation and metastasis by targeting deleted in liver cancer-1 and runt-related transcription factor 3. J Cell Biochem. 2018;120:6078–89.
Google Scholar
Hu J, Ruan J, Liu X, Xiao C, Xiong J. MicroRNA-301a-3p suppressed the progression of hepatocellular carcinoma via targeting VGLL4. Pathol Res Pract. 2018;214:2039–45.
Google Scholar
Wu H-T, Xie C-R, Lv J, Qi H-Q, Wang F, Zhang S, et al. The tumor suppressor DLC1 inhibits cancer progression and oncogenic autophagy in hepatocellular carcinoma. Lab Investig. 2018;98:1014–24.
Google Scholar
Li S, Dong F, Wu Y, Zhang S, Zhang C, Liu X, et al. A deep boosting based approach for capturing the sequence binding preferences of RNA-binding proteins from high-throughput CLIP-seq data. Nucleic Acids Res. 2017;45:e129.
Google Scholar
Chuong E, Liu Q, Liu Y, Mao Y, Yi D, Li Q, et al. Maximal inhibitory effect of MOV10 on LINE-1 retrotransposition requires both the MOV10/LINE-1 association and granule formation. PLoS Genet. 2025;21:e1011709.
Xue GP, Faber GP, Pommerening LS, Mallick M, Gupta A, Wahl MC, et al. Functional investigation of the RNA helicase MOV10 with respect to its interplay with factors involved in nonsense-mediated mRNA decay. J Biol Chem. 2025;301:110418.
Gregersen LeaH, Schueler M, Munschauer M, Mastrobuoni G, Chen W, Kempa S, et al. MOV10 is a 5′ to 3′ RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3′ UTRs. Mol Cell. 2014;54:573–85.
Google Scholar
Yu J, Yang M, Zhou B, Luo J, Zhang Z, Zhang W, et al. CircRNA-104718 acts as competing endogenous RNA and promotes hepatocellular carcinoma progression through microRNA-218-5p/TXNDC5 signaling pathway. Clin Sci. 2019;133:1487–503.
Google Scholar
Zhang P-F, Wei C-Y, Huang X-Y, Peng R, Yang X, Lu J-C, et al. Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression. Mol Cancer. 2019;18:105.
Fu K, Tian S, Tan H, Wang C, Wang H, Wang M, et al. Biological and RNA regulatory function of MOV10 in mammalian germ cells. BMC Biol. 2019;17:39.
Nawaz A, Shilikbay T, Skariah G, Ceman S. Unwinding the roles of RNAhelicaseMOV10. WIREs RNA. 2021;13:e1682.
Abuduwaili K, Zhu X, Shen Y, Lu S, Liu C. circ_0008797 attenuates non-small cell lung cancer proliferation, metastasis, and aerobic glycolysis by sponging miR-301a-3p/SOCS2. Environ Toxicol. 2022;37:1697–710.
Google Scholar
