Competing interests
OP reports research funding from Bristol Myers Squibb, Takeda, and Janssen. BAC reports research funding from Genentech. KKP reports consulting fees from Celgene, Bristol Myers Squibb, Janssen, Pfizer, Merck, Takeda, AbbVie, AstraZeneca, Legend Biotech, Novartis, and Regeneron, and research funding from Celgene, Bristol Myers Squibb, Janssen, Nektar, AbbVie, Genentech, and Indapta Therapeutics. HCL reports consulting fees from Alexion Pharmaceuticals, Bristol Myers Squibb, Janssen, Regeneron, GlaxoSmithKline, Sanofi, Takeda, Allogene Therapeutics, Pfizer, and Menarini, and research funding from Amgen, Bristol Myers Squibb, Janssen, GlaxoSmithKline, Regeneron, Takeda, and Alexion Pharmaceuticals. GPK is an employee of Kelonia Therapeutics, unrelated to the scope of this work. SKT reports consulting fees from AbbVie, Cellectar Biosciences, and Mustang Bio, and research funding from AbbVie, Ascentage Pharma, Acerta Pharma, Bristol Myers Squibb, Cellectar Biosciences, Genentech, Janssen, Sanofi, and X4 Pharma. RZO is a founder of Asylia Therapeutics with an equity interest, and reports consulting fees from Amgen, Bristol Myers Squibb, Celgene, EcoR1 Capital, Forma Therapeutics, Genzyme, GlaxoSmithKline, Ionis Pharmaceuticals, Janssen, Juno Therapeutics, Kite Pharma, Legend Biotech, Molecular Partners, Sanofi, Servier, and Takeda, and research funding from Asylia Therapeutics, BioTheryX, Heidelberg Pharma AG, and Genentech. MHQ reports research funding from Amgen, Angiocrine Bioscience, BioLineRx, Janssen, and NexImmune. The remaining authors declare no competing interests.
Ethics approval and consent to participate
All methods in this study were performed in accordance with the Declaration of Helsinki and the Health Insurance Portability and Accountability Act. Approval to conduct the study was attained from the Institutional Review Board (IRB) of the University of Texas MD Anderson Cancer Center (protocol ID: 2016-0681) and is registered at clinicaltrials.gov (ID: NCT03622775). Informed consent was obtained from all participants.
