Bernard E, Tuechler H, Greenberg Peter L, Hasserjian Robert P, Arango Ossa Juan E, Nannya Y, et al. Molecular international prognostic scoring system for myelodysplastic syndromes. NEJM Evid. 2022;1:EVIDoa2200008.
Google ScholarÂ
Cargo C, Bernard E, Beinortas T, Bolton KL, Glover P, Warren H, et al. Predicting cytopenias, progression, and survival in patients with clonal cytopenia of undetermined significance: a prospective cohort study. Lancet Haematol. 2024;11:e51–e61.
Google ScholarÂ
Huber S, Baer C, Hutter S, Wossidlo N, Hoermann G, Pohlkamp C, et al. Genomic landscape of CCUS compared to MDS and its implications on risk prediction. Leukemia. 2024;38:1634–7.
Google ScholarÂ
Nazha A, Sekeres MA, Bejar R, Rauh MJ, Othus M, Komrokji RS, et al. Genomic biomarkers to predict resistance to hypomethylating agents in patients with myelodysplastic syndromes using artificial intelligence. JCO Precis Oncol. 2019;3:PO.19.00119.
Google ScholarÂ
Polprasert C, Niparuck P, Rattanathammethee T, Chuncharunee S, Kobbuaklee S, Songserm K, et al. Excellent prognosis of low-risk myelodysplastic syndromes (MDS) without detectable myeloid-related mutations. Clin Lymphoma Myeloma Leuk. 2022;22:e293–e9.
Google ScholarÂ
Huber S, Haferlach T, Müller H, Meggendorfer M, Hutter S, Hoermann G, et al. MDS subclassification-do we still have to count blasts? Leukemia. 2023;37:942–5.
Google ScholarÂ
Wang SA, Ok CY, Kim AS, Lucas F, Morgan EA, Thakral B, et al. Myelodysplastic syndromes with no somatic mutations detected by next-generation sequencing display similar features to myelodysplastic syndromes with detectable mutations. Am J Hematol. 2021;96:E420–e3.
Google ScholarÂ
Khoury JD, Solary E, Abla O, Akkari Y, Alaggio R, Apperley JF, et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia. 2022;36:1703–19.
Google ScholarÂ
Sondka Z, Bamford S, Cole CG, Ward SA, Dunham I, Forbes SA. The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers. Nat Rev Cancer. 2018;18:696–705.
Google ScholarÂ
Lee WH, Lin C-C, Tsai C-H, Tien F-M, Lo MY, Tseng M-H, et al. Clinical characteristics and prognostic implications for myelodysplastic syndromes/neoplasms patients with or without cytogenetic abnormalities or gene mutations. Blood. 2024;144:6752.
Google ScholarÂ
Arber DA, Orazi A, Hasserjian RP, Borowitz MJ, Calvo KR, Kvasnicka HM, et al. International consensus classification of myeloid neoplasms and acute leukemia: integrating morphological, clinical, and genomic data. Blood. 2022;140:1200–28.
Greenberg PL, Stone RM, Abaza Y, Al-Kali A, Anand S, Ball B, et al. NCCN Guidelines® Insights: Myelodysplastic Syndromes, Version 2.2025. J Natl Compr Canc Netw. 2025;23:66–75.
Google ScholarÂ
Meggendorfer M, Walter W, Nadarajah N, Haferlach C, Kern W, Haferlach T. Cracking a nut with a sledgehammer? – Broadening the spectrum of gene mutation analysis in MDS does not add clinically relevant information. Blood. 2020;136:30.
Google ScholarÂ

