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Browsing: PanMutantSelective

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98 A Phase 1/2 Trial of LY4064809, A Pan-Mutant-Selective PI3Kα Inhibitor in HR+/HER2− Advanced Breast Cancer, Updated Results From PIKALO-1

By NewsCancerMay 22, 20260

BackgroundPI3Kα inhibitors (PI3Kαi) demonstrated clinical benefit in approximately 40% of patients with hormone receptor–positive/HER2-negative (HR+/HER2–) advanced breast cancer with PIK3CA…

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Neoadjuvant triplet chemotherapy enables radiotherapy avoidance in human papillomavirus–associated oropharyngeal cancer: a multicentre Phase II trial

Translational modelling challenges receptor‑occupancy‑based dosing of PD‑1 inhibitors like pembrolizumab

A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions

Browsing: PanMutantSelective

98 A Phase 1/2 Trial of LY4064809, A Pan-Mutant-Selective PI3Kα Inhibitor in HR+/HER2− Advanced Breast Cancer, Updated Results From PIKALO-1

Neoadjuvant triplet chemotherapy enables radiotherapy avoidance in human papillomavirus–associated oropharyngeal cancer: a multicentre Phase II trial

Translational modelling challenges receptor‑occupancy‑based dosing of PD‑1 inhibitors like pembrolizumab

A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions

How Might WCLC 2026 Clarify the Evolving Role of APPs in Lung Cancer?

Neoadjuvant triplet chemotherapy enables radiotherapy avoidance in human papillomavirus–associated oropharyngeal cancer: a multicentre Phase II trial

Translational modelling challenges receptor‑occupancy‑based dosing of PD‑1 inhibitors like pembrolizumab

A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions

How Might WCLC 2026 Clarify the Evolving Role of APPs in Lung Cancer?

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Neoadjuvant triplet chemotherapy enables radiotherapy avoidance in human papillomavirus–associated oropharyngeal cancer: a multicentre Phase II trial

Translational modelling challenges receptor‑occupancy‑based dosing of PD‑1 inhibitors like pembrolizumab

A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions

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Browsing: PanMutantSelective