Author: NewsCancer

Is sugar bad for you? Can it really have a head-to-toe impact on the human body? When we’re talking about added sugar, the answer is a resounding “yes.” We know that sugar impacts just about every organ system in the body … and not in a good way. Let’s take a look at the top ways added sugar destroys your body and ways to cut down on your intake so you can avoid sugar addiction and the negative effects added sugar has on health. Is sugar bad for you? Health effects Yes, sugar can be bad for you, especially added sugar.…

The Cancerwise podcast features insights from MD Anderson experts on cancer diagnosis and treatment, research breakthroughs, and prevention, as well as stories from survivors and caregivers who’ve faced cancer firsthand. The Cancerwise podcast features insights from MD Anderson experts on cancer diagnosis and treatment, research breakthroughs, and prevention, as well as stories from survivors and caregivers who’ve faced cancer firsthand.

If MMA fuels malignancy, could its depletion starve it? Miao et al. [5] take their fundamental concepts and apply them in a clever intervention strategy. They took inspiration from the clinical dietary management of patients with methylmalonic acidemia and placed ccRCC-bearing mice under a low-BCAA diet to reduce MMA availability. This simple dietary change worked therapeutically to not only diminish tumor growth but also reduce pulmonary metastases and limit M2 macrophage infiltration. This reinforces the idea that a net metabolic shift in the diet can therapeutically restrain the immune system, and whether MMA could contribute to immune evasion or resistance…

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74:229–63.PubMed  Google Scholar  Rumgay H, Ferlay J, de Martel C, Georges D, Ibrahim AS, Zheng R, et al. Global, regional and national burden of primary liver cancer by subtype. Eur J Cancer. 2022;161:108–18.Article  PubMed  Google Scholar  Zheng J, Wang S, Xia L, Sun Z, Chan KM, Bernards R, et al. Hepatocellular carcinoma: signaling pathways and therapeutic advances. Signal Transduct Target Ther. 2025;10:35.Article  PubMed  PubMed Central …

Sortilin and EGFR nuclear interaction in EGF-stimulated cellsBased on findings showing that sortilin limits EGFR proliferative signaling [18, 19], we tested whether sortilin exhibits a tumor suppressor-like activity by acting on its nuclear signaling network. Although sortilin physically interacts with EGFR at or near the plasma membrane in A549 cells, as previously reported [18, 19], we also detected EGFR–sortilin complexes toward the nuclei of cancer cells, following EGF stimulation, as shown by red spots indicating sites of proximity ligation amplification (PLA) (Fig. 1a; insets 1.1 to 2.2). Z-stack confocal images and three-dimensional projections at 90° and 155° confirmed that EGFR–sortilin…

Elliss-Brookes L, McPhail S, Ives A, Greenslade M, Shelton J, Hiom S, et al. Routes to diagnosis for cancer – determining the patient journey using multiple routine data sets. Br J Cancer. 2012;107:1220–6.Article  CAS  PubMed  PubMed Central  Google Scholar  McPhail S, Swann R, Johnson SA, Barclay ME, Abd Elkader H, Alvi R, et al. Risk factors and prognostic implications of diagnosis of cancer within 30 days after an emergency hospital admission (emergency presentation): an International Cancer Benchmarking Partnership (ICBP) population-based study. Lancet Oncol. 2022;23:587–600.Article  CAS  PubMed  PubMed Central  Google Scholar  McPhail S, Elliss-Brookes L, Shelton J, Ives A, Greenslade M,…

Investigators and clinicians gathered in Salt Lake City for the 2026 Tandem Meetings amid rapid evolution in cellular therapy. Across lymphoma, leukemia, multiple myeloma, and transplant-related infectious complications, the most anticipated presentations reflected a consistent theme: moving beyond proof-of-concept toward platform refinement by improving safety, shortening manufacturing timelines, and expanding access to patients who have historically been unable to receive these therapies.From next-generation CAR-T constructs delivering deep responses with markedly improved toxicity profiles to immune-cloaked allogeneic products designed to scale “off the shelf,” here are 6 clinically oriented abstracts that may shape near-term practice.What to Watch in Aggressive B-Cell LymphomaLate-Breaking: EB-103…

By Deanna Neff HealthDay ReporterFRIDAY, Feb. 13, 2026 (HealthDay News) — For many, hair extensions are a staple of style and convenience, but they may come with a hidden health cost.Researchers have uncovered a wide array of hazardous chemicals in these products — including those linked to cancer and birth defects — marking the most comprehensive look to date at this largely unregulated industry.The study — published Feb. 11 in Environment & Health — highlights a significant public health gap. While hair extensions are a multi-billion-dollar global market, there is very little oversight of what goes into the fibers. This lack…

The American Cancer Society recently published an article detailing the intricacies of cancer incidence, and despite advancements in the understanding of tumor biology, the 5-year survival rate for pancreatic cancer remains at 13%, significantly lagging behind the 70% survival rate observed across all combined cancer types.1 The PRECEDE Consortium aims to transform the clinical trajectory for patients with pancreatic cancer by establishing a global infrastructure for early detection and data sharing, according to Diane Simeone, MD.In a conversation with CancerNetwork, Simeone, the director of the Moores Cancer Center at the University of California San Diego Health, discussed this effort and…

By Dennis Thompson HealthDay ReporterFRIDAY, Feb. 13, 2026 (HealthDay News) — Rural cancer patients often travel long distances to seek treatment at major medical centers, but new research suggests those journeys might not be necessary.Lung or colon cancer patients treated at a local hospital had similar death rates and surgical outcomes to those who traveled to big-city medical centers for care, researchers reported Feb. 11 in the Journal of the American College of Surgeons.The results provide promising preliminary evidence that complex surgery for some cancers can be performed just as well at smaller community hospitals, researchers said.“Cancer patients in rural…